Recent Advances in Glycopolymers Based on Protecting-Group-Free Synthesis
نویسندگان
چکیده
منابع مشابه
Recent Advances in Metal-Free Quinoline Synthesis.
The quinoline ring system is one of the most ubiquitous heterocycles in the fields of medicinal and industrial chemistry, forming the scaffold for compounds of great significance. These include anti-inflammatory and antitumor agents, the antimalarial drugs quinine and chloroquine, and organic light-emitting diodes. Quinolines were first synthesized in 1879, and since then a multitude of synthet...
متن کاملOne-step protecting-group-free synthesis of azepinomycin in water.
We report an efficient, atom economical general acid-base catalyzed one-step multi-gram synthesis of azepinomycin from commercially available compounds in water. We propose that the described pH-dependent Amadori rearrangement, which couples an amino-imidazole and simple sugar, is of importance as a potential step toward predisposed purine nucleotide synthesis at the origins of life.
متن کاملStepwise, Protecting Group Free Synthesis of [4]Rotaxanes.
Despite significant advances in the last three decades towards high yielding syntheses of rotaxanes, the preparation of systems constructed from more than two components remains a challenge. Herein we build upon our previous report of an active template copper-catalyzed azide-alkyne cycloaddition (CuAAC) rotaxane synthesis with a diyne in which, following the formation of the first mechanical b...
متن کاملProtecting-group-free synthesis of 2-deoxy-aza-sugars.
The protecting-group-free asymmetric synthesis of 1,2,4-trideoxy-1,4-imino-L-xylitol is readily achieved in five steps from 2-deoxy-D-ribose and with an overall yield of 48%. Key in this synthesis is the application of our recently developed Vasella-reductive amination and carbamate annulation methodologies to the synthesis of 2-deoxy-aza-sugars. The carbamate annulation occurred with excellent...
متن کاملThe catalytic enantioselective, protecting group-free total synthesis of (+)-dichroanone.
Herein we report the first enantioselective total synthesis of (+)-dichroanone, confirming the absolute configuration of the natural product. This protecting group-free route features the first application of our enantioselective Tsuji allylation in the context of a natural product total synthesis. Additionally, this 11-step preparation of the molecule from commercial material features a novel ...
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ژورنال
عنوان ژورنال: KOBUNSHI RONBUNSHU
سال: 2016
ISSN: 0386-2186,1881-5685
DOI: 10.1295/koron.2016-0020